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ITPRs/inositol 1,4,5-trisphosphate receptors in autophagy: From enemy to ally

ITPRs (inositol 1,4,5-trisphosphate receptors), the main endoplasmic reticulum (ER) Ca(2+)-release channels, were originally proposed as suppressors of autophagy. Yet, new evidence has accumulated over recent years supporting a crucial, stimulatory role for ITPRs in driving the autophagic flux. Here...

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Detalles Bibliográficos
Autores principales:	Decuypere, Jean-Paul, Parys, Jan B, Bultynck, Geert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Views and Commentaries
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824608/ https://www.ncbi.nlm.nih.gov/pubmed/26291777 http://dx.doi.org/10.1080/15548627.2015.1083666

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