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Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis

Increased Src activity has been associated with the pathogenesis of renal tumors and some glomerular diseases, but its role in renal interstitial fibrosis remains elusive. To evaluate this, cultured renal interstitial fibroblasts (NRK-49F) were treated with PP1, a selective inhibitor of Src. This re...

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Detalles Bibliográficos
Autores principales:	Yan, Yanli, Ma, Li, Zhou, Xiaoxu, Ponnusamy, Murugavel, Tang, Jinhua, Zhuang, Michelle A., Tolbert, Evelyn, Bayliss, Georgia, Bai, Jianwen, Zhuang, Shougang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824676/ https://www.ncbi.nlm.nih.gov/pubmed/26444028 http://dx.doi.org/10.1038/ki.2015.293

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