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Five biopsy specimens from the proximal part of the tumor reliably determine HER2 protein expression status in gastric cancer
BACKGROUND: National guidelines recommend trastuzumab for treatment of patients with metastatic HER2-positive gastric cancer (GC). There is currently no guideline indicating the number of biopsy specimens and the location from which they should be obtained to reliably determine the human epidermal g...
Autores principales: | Tominaga, Naoyuki, Gotoda, Takuji, Hara, Megumi, Hale, Matthew D., Tsuchiya, Takayoshi, Matsubayashi, Jun, Kono, Shin, Kusano, Chika, Itoi, Takao, Fujimoto, Kazuma, Moriyasu, Fuminori, Grabsch, Heike I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Japan
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824804/ https://www.ncbi.nlm.nih.gov/pubmed/25987463 http://dx.doi.org/10.1007/s10120-015-0502-3 |
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