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Binding of Hyaluronan to the Native Lymphatic Vessel Endothelial Receptor LYVE-1 Is Critically Dependent on Receptor Clustering and Hyaluronan Organization

The lymphatic endothelial receptor LYVE-1 has been implicated in both uptake of hyaluronan (HA) from tissue matrix and in facilitating transit of leukocytes and tumor cells through lymphatic vessels based largely on in vitro studies with recombinant receptor in transfected fibroblasts. Curiously, ho...

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Detalles Bibliográficos
Autores principales: Lawrance, William, Banerji, Suneale, Day, Anthony J., Bhattacharjee, Shaumick, Jackson, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825007/
https://www.ncbi.nlm.nih.gov/pubmed/26823460
http://dx.doi.org/10.1074/jbc.M115.708305