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Replicates and repeats

The authors of this paper were interested to see whether the expression of three proteins (A, B and C) was altered in a knockout mouse model of a gene encoding Protein X. Each experiment measured the expression of a different protein and the results seem to show a clear increase in protein expressio...

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Detalles Bibliográficos
Autor principal: Bell, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825082/
https://www.ncbi.nlm.nih.gov/pubmed/27055650
http://dx.doi.org/10.1186/s12915-016-0254-5
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author Bell, Graham
author_facet Bell, Graham
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description The authors of this paper were interested to see whether the expression of three proteins (A, B and C) was altered in a knockout mouse model of a gene encoding Protein X. Each experiment measured the expression of a different protein and the results seem to show a clear increase in protein expression in the mutant mouse compared with the control. The results are reported as statistically significant, with impressive ‘n’ values in each condition: the authors say that n = 7 in each case. They confidently conclude that the level of each of the three proteins is increased in the knockout mutant.
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spelling pubmed-48250822016-04-09 Replicates and repeats Bell, Graham BMC Biol Comment The authors of this paper were interested to see whether the expression of three proteins (A, B and C) was altered in a knockout mouse model of a gene encoding Protein X. Each experiment measured the expression of a different protein and the results seem to show a clear increase in protein expression in the mutant mouse compared with the control. The results are reported as statistically significant, with impressive ‘n’ values in each condition: the authors say that n = 7 in each case. They confidently conclude that the level of each of the three proteins is increased in the knockout mutant. BioMed Central 2016-04-07 /pmc/articles/PMC4825082/ /pubmed/27055650 http://dx.doi.org/10.1186/s12915-016-0254-5 Text en © Bell. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Comment
Bell, Graham
Replicates and repeats
title Replicates and repeats
title_full Replicates and repeats
title_fullStr Replicates and repeats
title_full_unstemmed Replicates and repeats
title_short Replicates and repeats
title_sort replicates and repeats
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825082/
https://www.ncbi.nlm.nih.gov/pubmed/27055650
http://dx.doi.org/10.1186/s12915-016-0254-5
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