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Hematobiochemical changes in ehrlichiosis in dogs of Anand region, Gujarat

AIM: The present research work was undertaken to study the diagnostic importance of hematobiochemical changes in naturally occurring ehrlichiosis in dogs of Anand region, Gujarat irrespective of their age, breed, and sex. MATERIALS AND METHODS: Blood samples from a total of 29 dogs of Anand region o...

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Autores principales: Bhadesiya, C. M., Raval, S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Veterinary World 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825270/
https://www.ncbi.nlm.nih.gov/pubmed/27065635
http://dx.doi.org/10.14202/vetworld.2015.713-717
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author Bhadesiya, C. M.
Raval, S. K.
author_facet Bhadesiya, C. M.
Raval, S. K.
author_sort Bhadesiya, C. M.
collection PubMed
description AIM: The present research work was undertaken to study the diagnostic importance of hematobiochemical changes in naturally occurring ehrlichiosis in dogs of Anand region, Gujarat irrespective of their age, breed, and sex. MATERIALS AND METHODS: Blood samples from a total of 29 dogs of Anand region of Gujarat state were screened for detection of anti-Ehrlichia canis antibodies using Immunocomb(®) rapid diagnostic kit (Biogal Galed Laboratories, Israel) and subjected to estimation of hematobiochemical parameters by auto hematology analyzers at College of Veterinary Science and Animal Husbandry, Anand. Statistical analysis, interpretation and comparison of hematobiochemical changes with scientific literature was carried out in order to understand the pathophysiology of the disease. RESULTS: Of 29 dogs, 18 were positive for naturally occurring ehrlichiosis based on the presence of anti-E. canis antibodies while 11 were negative. Haematology evinced that the mean values of hemoglobin, total erythrocyte counts, platelet count and packed cell volume in dogs with ehrlichiosis decreased significantly (p<0.01) in comparison to healthy dogs. Among differential leucocyte count, mean values of lymphocytes decreased, neutrophils increased, eosinophils decreased and basophils decreased significantly (p<0.05) in dogs with ehrlichiosis in comparison to healthy dogs while statistically non-significant (p>0.05) difference was observed in values of monocytes in dogs with ehrlichiosis and healthy dogs. Among various red blood cells indices, the mean values of mean corpuscular hemoglobin concentration increased significantly (p<0.01) in dogs with ehrlichiosis in comparison to healthy dogs. Serum biochemistry revealed significant (p<0.01) increase in serum glutamic pyruvic transaminase, serum glutamic oxaloacetic transaminase and creatinine levels as well as decrease in total protein levels in dogs with ehrlichiosis as compared to healthy dogs. CONCLUSION: Clinical importance of hematobiochemical changes in 18 natural cases of ehrlichiosis in dogs of Anand region, Gujarat irrespective of their age, breed and sex is discussed, which would aid new insights in diagnosis and therapeutic management.
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spelling pubmed-48252702016-04-08 Hematobiochemical changes in ehrlichiosis in dogs of Anand region, Gujarat Bhadesiya, C. M. Raval, S. K. Vet World Research Article AIM: The present research work was undertaken to study the diagnostic importance of hematobiochemical changes in naturally occurring ehrlichiosis in dogs of Anand region, Gujarat irrespective of their age, breed, and sex. MATERIALS AND METHODS: Blood samples from a total of 29 dogs of Anand region of Gujarat state were screened for detection of anti-Ehrlichia canis antibodies using Immunocomb(®) rapid diagnostic kit (Biogal Galed Laboratories, Israel) and subjected to estimation of hematobiochemical parameters by auto hematology analyzers at College of Veterinary Science and Animal Husbandry, Anand. Statistical analysis, interpretation and comparison of hematobiochemical changes with scientific literature was carried out in order to understand the pathophysiology of the disease. RESULTS: Of 29 dogs, 18 were positive for naturally occurring ehrlichiosis based on the presence of anti-E. canis antibodies while 11 were negative. Haematology evinced that the mean values of hemoglobin, total erythrocyte counts, platelet count and packed cell volume in dogs with ehrlichiosis decreased significantly (p<0.01) in comparison to healthy dogs. Among differential leucocyte count, mean values of lymphocytes decreased, neutrophils increased, eosinophils decreased and basophils decreased significantly (p<0.05) in dogs with ehrlichiosis in comparison to healthy dogs while statistically non-significant (p>0.05) difference was observed in values of monocytes in dogs with ehrlichiosis and healthy dogs. Among various red blood cells indices, the mean values of mean corpuscular hemoglobin concentration increased significantly (p<0.01) in dogs with ehrlichiosis in comparison to healthy dogs. Serum biochemistry revealed significant (p<0.01) increase in serum glutamic pyruvic transaminase, serum glutamic oxaloacetic transaminase and creatinine levels as well as decrease in total protein levels in dogs with ehrlichiosis as compared to healthy dogs. CONCLUSION: Clinical importance of hematobiochemical changes in 18 natural cases of ehrlichiosis in dogs of Anand region, Gujarat irrespective of their age, breed and sex is discussed, which would aid new insights in diagnosis and therapeutic management. Veterinary World 2015-06 2015-06-06 /pmc/articles/PMC4825270/ /pubmed/27065635 http://dx.doi.org/10.14202/vetworld.2015.713-717 Text en Copyright: © The authors. http://creativecommons.org/licenses/by/2.0 This article is an open access article licensed under the terms of the Creative Commons Attributin License (http://creative commons.org/licenses/by/2.0) which permits unrestricted use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Research Article
Bhadesiya, C. M.
Raval, S. K.
Hematobiochemical changes in ehrlichiosis in dogs of Anand region, Gujarat
title Hematobiochemical changes in ehrlichiosis in dogs of Anand region, Gujarat
title_full Hematobiochemical changes in ehrlichiosis in dogs of Anand region, Gujarat
title_fullStr Hematobiochemical changes in ehrlichiosis in dogs of Anand region, Gujarat
title_full_unstemmed Hematobiochemical changes in ehrlichiosis in dogs of Anand region, Gujarat
title_short Hematobiochemical changes in ehrlichiosis in dogs of Anand region, Gujarat
title_sort hematobiochemical changes in ehrlichiosis in dogs of anand region, gujarat
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825270/
https://www.ncbi.nlm.nih.gov/pubmed/27065635
http://dx.doi.org/10.14202/vetworld.2015.713-717
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