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SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status

Seven-in-absentia homolog (SIAH) proteins are evolutionary conserved RING type E3 ubiquitin ligases responsible for the degradation of key molecules regulating DNA damage response, hypoxic adaptation, apoptosis, angiogenesis, and cell proliferation. Many studies suggest a tumorigenic role for SIAH2....

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Detalles Bibliográficos
Autores principales: Adam, M Gordian, Matt, Sonja, Christian, Sven, Hess-Stumpp, Holger, Haegebarth, Andrea, Hofmann, Thomas G, Algire, Carolyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825722/
https://www.ncbi.nlm.nih.gov/pubmed/26654769
http://dx.doi.org/10.1080/15384101.2015.1104441

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