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Engineered Aminoacyl-tRNA Synthetase for Cell-Selective Analysis of Mammalian Protein Synthesis

[Image: see text] Methods for cell-selective analysis of proteome dynamics will facilitate studies of biological processes in multicellular organisms. Here we describe a mutant murine methionyl-tRNA synthetase (designated L274GMmMetRS) that charges the noncanonical amino acid azidonorleucine (Anl) t...

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Detalles Bibliográficos
Autores principales:	Mahdavi, Alborz, Hamblin, Graham D., Jindal, Granton A., Bagert, John D., Dong, Cathy, Sweredoski, Michael J., Hess, Sonja, Schuman, Erin M., Tirrell, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2016
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825725/ https://www.ncbi.nlm.nih.gov/pubmed/26991063 http://dx.doi.org/10.1021/jacs.5b08980

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