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Tetraploidization or autophagy: The ultimate fate of senescent human endometrial stem cells under ATM or p53 inhibition

Previously we demonstrated that endometrium-derived human mesenchymal stem cells (hMESCs) via activation of the ATM/p53/p21/Rb pathway enter the premature senescence in response to oxidative stress. Down regulation effects of the key components of this signaling pathway, particularly ATM and p53, on...

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Detalles Bibliográficos
Autores principales:	Borodkina, Aleksandra V., Shatrova, Alla N., Deryabin, Pavel I., Grukova, Anastasiya A., Nikolsky, Nikolay N., Burova, Elena B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825783/ https://www.ncbi.nlm.nih.gov/pubmed/26636375 http://dx.doi.org/10.1080/15384101.2015.1121326

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