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Coordinating cell proliferation and differentiation: Antagonism between cell cycle regulators and cell type-specific gene expression
Cell proliferation and differentiation show a remarkable inverse relationship. Precursor cells continue division before acquiring a fully differentiated state, while terminal differentiation usually coincides with proliferation arrest and permanent exit from the division cycle. Mechanistic insight i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825819/ https://www.ncbi.nlm.nih.gov/pubmed/26825227 http://dx.doi.org/10.1080/15384101.2015.1120925 |