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PUMA: a puzzle piece in chloroquine’s antimelanoma activity
Chloroquine can induce cell death in a subset of cancer cell lines, and some melanoma cell lines are quite susceptible. While it is well known that chloroquine impairs lysosomal function and can serve as an autophagy inhibitor, the molecular target of chloroquine and the subsequent cascade of events...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825873/ https://www.ncbi.nlm.nih.gov/pubmed/23949767 http://dx.doi.org/10.1038/jid.2013.135 |