FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection

The immune mechanisms that recognize inhaled Aspergillus fumigatus conidia to promote their elimination from the lungs are incompletely understood. FleA is a lectin expressed by Aspergillus fumigatus that has twelve binding sites for fucosylated structures that are abundant in the glycan coats of mu...

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Detalles Bibliográficos
Autores principales: Kerr, Sheena C., Fischer, Gregory J., Sinha, Meenal, McCabe, Orla, Palmer, Jonathan M., Choera, Tsokyi, Yun Lim, Fang, Wimmerova, Michaela, Carrington, Stephen D., Yuan, Shaopeng, Lowell, Clifford A., Oscarson, Stefan, Keller, Nancy P., Fahy, John V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825926/
https://www.ncbi.nlm.nih.gov/pubmed/27058347
http://dx.doi.org/10.1371/journal.ppat.1005555

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