Cargando…

Identification of Low- and High-Impact Hemagglutinin Amino Acid Substitutions That Drive Antigenic Drift of Influenza A(H1N1) Viruses

Determining phenotype from genetic data is a fundamental challenge. Identification of emerging antigenic variants among circulating influenza viruses is critical to the vaccine virus selection process, with vaccine effectiveness maximized when constituents are antigenically similar to circulating vi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harvey, William T., Benton, Donald J., Gregory, Victoria, Hall, James P. J., Daniels, Rodney S., Bedford, Trevor, Haydon, Daniel T., Hay, Alan J., McCauley, John W., Reeve, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825936/ https://www.ncbi.nlm.nih.gov/pubmed/27057693 http://dx.doi.org/10.1371/journal.ppat.1005526

Ejemplares similares

Biophysical Measurement of the Balance of Influenza A Hemagglutinin and Neuraminidase Activities
por: Benton, Donald J., et al.
Publicado: (2015)

A Bayesian approach to incorporate structural data into the mapping of genotype to antigenic phenotype of influenza A(H3N2) viruses
por: Harvey, William T., et al.
Publicado: (2023)

Natural and directed antigenic drift of the H1 influenza virus hemagglutinin stalk domain
por: Anderson, Christopher S., et al.
Publicado: (2017)

Global circulation patterns of seasonal influenza viruses vary with antigenic drift
por: Bedford, Trevor, et al.
Publicado: (2015)

Limited Predictability of Amino Acid Substitutions in Seasonal Influenza Viruses
por: Barrat-Charlaix, Pierre, et al.
Publicado: (2021)

Publisher Correction: Natural and directed antigenic drift of the H1 influenza virus hemagglutinin stalk domain
por: Anderson, Christopher S., et al.
Publicado: (2018)

Publisher Correction: Natural and directed antigenic drift of the H1 influenza virus hemagglutinin stalk domain
por: Anderson, Christopher S., et al.
Publicado: (2018)

Amino acid substitutions in hemagglutinin of the 2009 pandemic influenza A(H1N1) viruses that might affect the viral antigenicity
por: Kosoltanapiwat, Nathamon, et al.
Publicado: (2014)

Substantial Antigenic Drift in the Hemagglutinin Protein of Swine Influenza A Viruses
por: Ryt-Hansen, Pia, et al.
Publicado: (2020)

Antigenic drift and subtype interference shape A(H3N2) epidemic dynamics in the United States
por: Perofsky, Amanda C, et al.
Publicado: (2023)

Identifying novel amino acid substitutions of hemagglutinin involved in virulence enhancement in H7N9 virus strains
por: Zhang, Ting, et al.
Publicado: (2021)

Antigenic Drift of the Hemagglutinin from an Influenza A (H1N1) pdm09 Clinical Isolate Increases its Pathogenicity In Vitro
por: Xing, Lei, et al.
Publicado: (2021)

Immune Escape Adaptive Mutations in Hemagglutinin Are Responsible for the Antigenic Drift of Eurasian Avian-Like H1N1 Swine Influenza Viruses
por: Xu, Chengzhi, et al.
Publicado: (2022)

A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea Pigs
por: Wang, Zeng, et al.
Publicado: (2017)

Influenza hemagglutinin membrane anchor
por: Benton, Donald J., et al.
Publicado: (2018)

A Sanger sequencing protocol for SARS‐CoV‐2 S‐gene
por: Daniels, Rodney S., et al.
Publicado: (2021)

Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020
por: Mohan, Teena, et al.
Publicado: (2021)

Patterns of Predicted T-Cell Epitopes Associated with Antigenic Drift in Influenza H3N2 Hemagglutinin
por: Homan, E. Jane, et al.
Publicado: (2011)

Neutralizing Epitopes and Residues Mediating the Potential Antigenic Drift of the Hemagglutinin-Esterase Protein of Influenza C Virus
por: Matsuzaki, Yoko, et al.
Publicado: (2018)

Assessing antigenic drift and phylogeny of influenza A (H1N1) pdm09 virus in Kenya using HA1 sub-unit of the hemagglutinin gene
por: Opanda, Silvanos, et al.
Publicado: (2020)

Integrating influenza antigenic dynamics with molecular evolution
por: Bedford, Trevor, et al.
Publicado: (2014)

The WHO global influenza surveillance and response system (GISRS)—A future perspective
por: Hay, Alan J, et al.
Publicado: (2018)

Genome-wide evolutionary dynamics of influenza B viruses on a global scale
por: Langat, Pinky, et al.
Publicado: (2017)

Rapid and parallel adaptive mutations in spike S1 drive clade success in SARS-CoV-2
por: Kistler, Kathryn E., et al.
Publicado: (2022)

Rapid and parallel adaptive mutations in spike S1 drive clade success in SARS-CoV-2
por: Kistler, Kathryn E., et al.
Publicado: (2022)

Radical Functionalization of Unsaturated Amino Acids: Synthesis of Side-Chain-Fluorinated, Azido-Substituted, and Hydroxylated Amino Acids
por: Reeve, Philip A. P., et al.
Publicado: (2019)

Antigenic and genetic characterization of influenza viruses circulating in Bulgaria during the 2015/2016 season
por: Korsun, Neli, et al.
Publicado: (2017)

A Single Amino Acid Substitution at Residue 218 of Hemagglutinin Improves the Growth of Influenza A(H7N9) Candidate Vaccine Viruses
por: Li, Xing, et al.
Publicado: (2019)

Accurate Measurement of the Effects of All Amino-Acid Mutations on Influenza Hemagglutinin
por: Doud, Michael B., et al.
Publicado: (2016)

A Single Residue Substitution in the Receptor-Binding Domain of H5N1 Hemagglutinin Is Critical for Packaging into Pseudotyped Lentiviral Particles
por: Tang, Dong-Jiang, et al.
Publicado: (2012)

Did Genetic Drift Drive Increases in Genome Complexity?
por: Whitney, Kenneth D., et al.
Publicado: (2010)

ncDNA and drift drive binding site accumulation
por: Ruths, Troy, et al.
Publicado: (2012)

Improving the representativeness of influenza viruses shared within the WHO Global Influenza Surveillance and Response System
por: Pereyaslov, Dmitriy, et al.
Publicado: (2016)

De-repression of the RAC activator ELMO1 in cancer stem cells drives progression of TGFβ-deficient squamous cell carcinoma from transition zones
por: McCauley, Heather A, et al.
Publicado: (2017)

Optimisation of a micro-neutralisation assay and its application in antigenic characterisation of influenza viruses
por: Lin, Yipu, et al.
Publicado: (2015)

A Novel I221L Substitution in Neuraminidase Confers High-Level Resistance to Oseltamivir in Influenza B Viruses
por: Escuret, Vanessa, et al.
Publicado: (2014)

Substitution Arg140Gly in Hemagglutinin Reduced the Virulence of Highly Pathogenic Avian Influenza Virus H7N1
por: Treshchalina, Anastasia, et al.
Publicado: (2021)

Mapping person-to-person variation in viral mutations that escape polyclonal serum targeting influenza hemagglutinin
por: Lee, Juhye M, et al.
Publicado: (2019)

Modeling the selective advantage of new amino acids on the hemagglutinin of H1N1 influenza viruses using their patient age distributions
por: Piantham, Chayada, et al.
Publicado: (2021)

Validating lane drifts as a predictive measure of drug or sleepiness induced driving impairment
por: Vinckenbosch, F. R. J., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5rrn1ls1ch9hpa5vvmpmr7jofi