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cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells

Human cytomegalovirus (HCMV) infections of healthy individuals are mostly unnoticed and result in viral latency. However, HCMV can also cause devastating disease, e.g., upon reactivation in immunocompromised patients. Yet, little is known about human immune cell sensing of DNA-encoded HCMV. Recent s...

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Detalles Bibliográficos
Autores principales:	Paijo, Jennifer, Döring, Marius, Spanier, Julia, Grabski, Elena, Nooruzzaman, Mohammed, Schmidt, Tobias, Witte, Gregor, Messerle, Martin, Hornung, Veit, Kaever, Volkhard, Kalinke, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825940/ https://www.ncbi.nlm.nih.gov/pubmed/27058035 http://dx.doi.org/10.1371/journal.ppat.1005546

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