Cargando…

Heterogeneity and chronology of 6q15 deletion and ERG-fusion in prostate cancer

Prostate cancer is notorious for its heterogeneity, which poses a problem for the applicability of diagnostic molecular markers. However, heterogeneity analysis can provide valuable information on the chronology in which molecular alterations arise. Here, we constructed a heterogeneity tissue microa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kluth, Martina, Meyer, David, Krohn, Antje, Freudenthaler, Fabian, Bauer, Melanie, Salomon, Georg, Heinzer, Hans, Michl, Uwe, Steurer, Stefan, Simon, Ronald, Sauter, Guido, Schlomm, Thorsten, Minner, Sarah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826178/ https://www.ncbi.nlm.nih.gov/pubmed/26684029 http://dx.doi.org/10.18632/oncotarget.6597

Ejemplares similares

Loss of CDKN1B/p27Kip1 expression is associated with ERG fusion-negative prostate cancer, but is unrelated to patient prognosis
por: SIRMA, HÜSEYIN, et al.
Publicado: (2013)

Loss of SOX9 Expression Is Associated with PSA Recurrence in ERG-Positive and PTEN Deleted Prostate Cancers
por: Burdelski, Christoph, et al.
Publicado: (2015)

The prognostic value of SUMO1/Sentrin specific peptidase 1 (SENP1) in prostate cancer is limited to ERG-fusion positive tumors lacking PTEN deletion
por: Burdelski, Christoph, et al.
Publicado: (2015)

Genomic deletion of chromosome 12p is an independent prognostic marker in prostate cancer
por: Kluth, Martina, et al.
Publicado: (2015)

Correction: Genomic deletion of chromosome 12p is an independent prognostic marker in prostate cancer
por: Kluth, Martina, et al.
Publicado: (2017)

Deletion of 18q is a strong and independent prognostic feature in prostate cancer
por: Kluth, Martina, et al.
Publicado: (2016)

Heterogeneity of ERG expression in prostate cancer: a large section mapping study of entire prostatectomy specimens from 125 patients
por: Tsourlakis, Maria-Christina, et al.
Publicado: (2016)

Deletion of 3p13 is a late event linked to progression of TMPRSS2:ERG fusion prostate cancer
por: Kluth, Martina, et al.
Publicado: (2018)

Upregulation of the heterogeneous nuclear ribonucleoprotein hnRNPA1 is an independent predictor of early biochemical recurrence in TMPRSS2:ERG fusion-negative prostate cancers
por: Möller, Katharina, et al.
Publicado: (2020)

High BCAR1 expression is associated with early PSA recurrence in ERG negative prostate cancer
por: Heumann, Asmus, et al.
Publicado: (2018)

High c-MET expression is frequent but not associated with early PSA recurrence in prostate cancer
por: JACOBSEN, FRANK, et al.
Publicado: (2013)

High concordance of TMPRSS-ERG fusion between primary prostate cancer and its lymph node metastases
por: Brandi, Franziska, et al.
Publicado: (2018)

High-Level γ-Glutamyl-Hydrolase (GGH) Expression is Linked to Poor Prognosis in ERG Negative Prostate Cancer
por: Melling, Nathaniel, et al.
Publicado: (2017)

Deletion lengthening at chromosomes 6q and 16q targets multiple tumor suppressor genes and is associated with an increasingly poor prognosis in prostate cancer
por: Kluth, Martina, et al.
Publicado: (2017)

Nuclear up regulation of the BRCA1-associated ubiquitinase BAP1 is associated with tumor aggressiveness in prostate cancers lacking the TMPRSS2:ERG fusion
por: Steurer, Stefan, et al.
Publicado: (2019)

Loss of PSP94 expression is associated with early PSA recurrence and deteriorates outcome of PTEN deleted prostate cancers
por: Luebke, Andreas M., et al.
Publicado: (2019)

Upregulation of the transcription factor TFAP2D is associated with aggressive tumor phenotype in prostate cancer lacking the TMPRSS2:ERG fusion
por: Fraune, Christoph, et al.
Publicado: (2020)

VEGFR-1 Overexpression Identifies a Small Subgroup of Aggressive Prostate Cancers in Patients Treated by Prostatectomy
por: Tsourlakis, Maria Christina, et al.
Publicado: (2015)

Secreted Frizzled-Related Protein 4 (SFRP4) Is an Independent Prognostic Marker in Prostate Cancers Lacking TMPRSS2: ERG Fusions
por: Bernreuther, Christian, et al.
Publicado: (2020)

Qualitative and Quantitative Requirements for Assessing Prognostic Markers in Prostate Cancer
por: Burdelski, Christoph, et al.
Publicado: (2014)

Overexpression of thymidylate synthase (TYMS) is associated with aggressive tumor features and early PSA recurrence in prostate cancer
por: Burdelski, Christoph, et al.
Publicado: (2015)

Deletion of 8p is an independent prognostic parameter in prostate cancer
por: Kluth, Martina, et al.
Publicado: (2016)

Up regulation and nuclear translocation of Y-box binding protein 1 (YB-1) is linked to poor prognosis in ERG-negative prostate cancer
por: Heumann, Asmus, et al.
Publicado: (2017)

HOXB13 overexpression is an independent predictor of early PSA recurrence in prostate cancer treated by radical prostatectomy
por: Zabalza, Cristina Villares, et al.
Publicado: (2015)

Author Correction: Up regulation and nuclear translocation of Y-box binding protein 1 (YB-1) is linked to poor prognosis in ERG-negative prostate cancer
por: Heumann, Asmus, et al.
Publicado: (2018)

Eolian chronology reveals causal links between tectonics, climate, and erg generation
por: Vainer, Shlomy, et al.
Publicado: (2022)

Family with sequence similarity 13C (FAM13C) overexpression is an independent prognostic marker in prostate cancer
por: Burdelski, Christoph, et al.
Publicado: (2017)

Up-regulation of Biglycan is Associated with Poor Prognosis and PTEN Deletion in Patients with Prostate Cancer
por: Jacobsen, Frank, et al.
Publicado: (2017)

Intragenic ERG Deletions Do Not Explain the Biology of ERG-Related Acute Lymphoblastic Leukemia
por: Potuckova, Eliska, et al.
Publicado: (2016)

Aberrant expression of the microtubule-associated protein tau is an independent prognostic feature in prostate cancer
por: Schroeder, Cornelia, et al.
Publicado: (2019)

Prognostic and diagnostic role of PSA immunohistochemistry: A tissue microarray study on 21,000 normal and cancerous tissues
por: Bonk, Sarah, et al.
Publicado: (2019)

Expression of CCCTC‐binding factor (CTCF) is linked to poor prognosis in prostate cancer
por: Höflmayer, Doris, et al.
Publicado: (2019)

Up regulation of Rho-associated coiled-coil containing kinase1 (ROCK1) is associated with genetic instability and poor prognosis in prostate cancer
por: Steurer, Stefan, et al.
Publicado: (2019)

TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling
por: Brase, Jan C, et al.
Publicado: (2011)

6q deletion is frequent but unrelated to patient prognosis in breast cancer
por: Lebok, Patrick, et al.
Publicado: (2021)

High-Level HOOK3 Expression Is an Independent Predictor of Poor Prognosis Associated with Genomic Instability in Prostate Cancer
por: Melling, Nathaniel, et al.
Publicado: (2015)

High mitochondria content is associated with prostate cancer disease progression
por: Grupp, Katharina, et al.
Publicado: (2013)

SNW1 is a prognostic biomarker in prostate cancer
por: Höflmayer, Doris, et al.
Publicado: (2019)

ERG Responses in Mice with Deletion of the Synaptic Ribbon Component RIBEYE
por: Fairless, Richard, et al.
Publicado: (2020)

Down-Regulation of S100A8 is an Independent Predictor of PSA Recurrence in Prostate Cancer Treated by Radical Prostatectomy()
por: Minner, Sarah, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_rh7ho8dfvg6ics4tetp70t91ql