Enhanced expression of LINE-1-encoded ORF2 protein in early stages of colon and prostate transformation

LINE-1 (L1) retrotransposons are a source of endogenous reverse transcriptase (RT) activity, which is expressed as part of the L1-encoded ORF2 protein (L1-ORF2p). L1 elements are highly expressed in many cancer types, while being silenced in most differentiated somatic tissues. We previously found t...

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Detalles Bibliográficos
Autores principales: De Luca, Chiara, Guadagni, Fiorella, Sinibaldi-Vallebona, Paola, Sentinelli, Steno, Gallucci, Michele, Hoffmann, Andreas, Schumann, Gerald G., Spadafora, Corrado, Sciamanna, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826189/
https://www.ncbi.nlm.nih.gov/pubmed/26716650
http://dx.doi.org/10.18632/oncotarget.6767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826189/
https://www.ncbi.nlm.nih.gov/pubmed/26716650
http://dx.doi.org/10.18632/oncotarget.6767

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