Cargando…

Enhanced expression of LINE-1-encoded ORF2 protein in early stages of colon and prostate transformation

LINE-1 (L1) retrotransposons are a source of endogenous reverse transcriptase (RT) activity, which is expressed as part of the L1-encoded ORF2 protein (L1-ORF2p). L1 elements are highly expressed in many cancer types, while being silenced in most differentiated somatic tissues. We previously found t...

Descripción completa

Detalles Bibliográficos
Autores principales:	De Luca, Chiara, Guadagni, Fiorella, Sinibaldi-Vallebona, Paola, Sentinelli, Steno, Gallucci, Michele, Hoffmann, Andreas, Schumann, Gerald G., Spadafora, Corrado, Sciamanna, Ilaria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826189/ https://www.ncbi.nlm.nih.gov/pubmed/26716650 http://dx.doi.org/10.18632/oncotarget.6767

Ejemplares similares

Retrotransposon-Encoded Reverse Transcriptase in the Genesis, Progression and Cellular Plasticity of Human Cancer
por: Sinibaldi-Vallebona, Paola, et al.
Publicado: (2011)

Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression
por: Gualtieri, Alberto, et al.
Publicado: (2013)

The Reverse Transcriptase Encoded by LINE-1 Retrotransposons in the Genesis, Progression, and Therapy of Cancer
por: Sciamanna, Ilaria, et al.
Publicado: (2016)

Regulatory roles of LINE-1-encoded reverse transcriptase in cancer onset and progression
por: Sciamanna, Ilaria, et al.
Publicado: (2014)

A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines
por: Sciamanna, Ilaria, et al.
Publicado: (2013)

HERV-K activation is strictly required to sustain CD133+ melanoma cells with stemness features
por: Argaw-Denboba, Ayele, et al.
Publicado: (2017)

An Epigenetic LINE-1-Based Mechanism in Cancer
por: Lavia, Patrizia, et al.
Publicado: (2022)

A Reverse Transcriptase-Dependent Mechanism Is Essential for Murine Preimplantation Development
por: Sciamanna, Ilaria, et al.
Publicado: (2011)

A re-evaluation of LINE-1 ORF2 expression in LNCaP prostate cancer cells
por: Briggs, Erica M., et al.
Publicado: (2019)

Transcriptional Activity of Human Endogenous Retroviruses in Human Peripheral Blood Mononuclear Cells
por: Balestrieri, Emanuela, et al.
Publicado: (2015)

Follicular dendritic cell sarcoma of the neck: Report of a case treated by surgical excision and COP plus (PEG)-liposomal doxorubicin
por: Pisani, Francesco, et al.
Publicado: (2008)

Endogenous Retroviruses Activity as a Molecular Signature of Neurodevelopmental Disorders
por: Balestrieri, Emanuela, et al.
Publicado: (2019)

AMBRA1 and SQSTM1 expression pattern in prostate cancer
por: Falasca, Laura, et al.
Publicado: (2015)

Long interspersed nuclear element-1 expression and retrotransposition in prostate cancer cells
por: Briggs, Erica M., et al.
Publicado: (2018)

Thymosin α1 Interacts with Hyaluronic Acid Electrostatically by Its Terminal Sequence LKEKK
por: Mandaliti, Walter, et al.
Publicado: (2017)

Orf-I and Orf-II-Encoded Proteins in HTLV-1 Infection and Persistence
por: Edwards, Dustin, et al.
Publicado: (2011)

PCA3 in prostate cancer and tumor aggressiveness detection on 407 high-risk patients: a National Cancer Institute experience
por: Merola, Roberta, et al.
Publicado: (2015)

Human Endogenous Retrovirus K in the Crosstalk Between Cancer Cells Microenvironment and Plasticity: A New Perspective for Combination Therapy
por: Balestrieri, Emanuela, et al.
Publicado: (2018)

HEV-ORF3 Encoding Phosphoprotein Interacts With Hepsin
por: Wang, Chunyan, et al.
Publicado: (2014)

Expression and detection of LINE-1 ORF-encoded proteins
por: Dai, Lixin, et al.
Publicado: (2014)

Identification of small ORF-encoded peptides in mouse serum
por: Deng, Yaqin, et al.
Publicado: (2018)

Sars Coronavirus Accessory ORFs Encode Luxury Functions
por: Frieman, Matthew B., et al.
Publicado: (2006)

Editorial: sORF Encoded Peptides in Health and Disease
por: Rothnagel, Joseph, et al.
Publicado: (2022)

Mesothelial cyst of the round ligament of the liver
por: Carboni, Fabio, et al.
Publicado: (2016)

Children With Autism Spectrum Disorder and Their Mothers Share Abnormal Expression of Selected Endogenous Retroviruses Families and Cytokines
por: Balestrieri, Emanuela, et al.
Publicado: (2019)

Testicular and inguinal lymph node metastases of medullary thyroid cancer: a case report and review of the literature
por: Appetecchia, Marialuisa, et al.
Publicado: (2014)

Characterization of proteins encoded by ORFs 2 to 7 of Lelystad virus
por: Meulenberg, Janneke J.M., et al.
Publicado: (1995)

Proposed Tandem Effect of Physical Activity and Sirtuin 1 and 3 Activation in Regulating Glucose Homeostasis
por: Pacifici, Francesca, et al.
Publicado: (2019)

Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response
por: Serafino, Annalucia, et al.
Publicado: (2008)

A putative new SARS-CoV protein, 3c, encoded in an ORF overlapping ORF3a
por: Firth, Andrew E.
Publicado: (2020)

The identification of viral ribonucleotide reductase encoded by ORF23 and ORF141 genes and effect on CyHV-2 replication
por: Cheng, Wenjie, et al.
Publicado: (2023)

Equid alphaherpesvirus 1 from Italian Horses: Evaluation of the Variability of the ORF30, ORF33, ORF34 and ORF68 Genes
por: Preziuso, Silvia, et al.
Publicado: (2019)

Moonlighting genes harbor antisense ORFs that encode potential membrane proteins
por: Thomas, Kasman E., et al.
Publicado: (2023)

Activation of human endogenous retrovirus K (HERV-K) and cellular modifications in human melanoma cell line: transcriptional profiling analysis
por: Balestrieri, Emanuela, et al.
Publicado: (2009)

High expression of Endogenous Retroviruses from intrauterine life to adulthood in two mouse models of Autism Spectrum Disorders
por: Cipriani, Chiara, et al.
Publicado: (2018)

The Decrease in Human Endogenous Retrovirus-H Activity Runs in Parallel with Improvement in ADHD Symptoms in Patients Undergoing Methylphenidate Therapy
por: Chiara, Cipriani, et al.
Publicado: (2018)

Orf – an orphan disease?
por: Meier, Rahel, et al.
Publicado: (2015)

Evolutionary Trends of the Transposase-Encoding Open Reading Frames A and B (orfA and orfB) of the Mycobacterial IS6110 Insertion Sequence
por: Thabet, Sara, et al.
Publicado: (2015)

Discovery of Human sORF-Encoded Polypeptides (SEPs) in Cell Lines and Tissue
por: Ma, Jiao, et al.
Publicado: (2014)

Detection and Analysis of C-to-U RNA Editing in Rice Mitochondria-Encoded ORFs
por: Zheng, Peng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_e53vsthl2egtdevt0qnk9toeqc