p130Cas scaffold protein regulates ErbB2 stability by altering breast cancer cell sensitivity to autophagy

Overexpression of the ErbB2/HER2 receptor tyrosine kinase occurs in up to 20% of human breast cancers and correlates with aggressive disease. Several efficacious targeted therapies, including antibodies and kinase inhibitors, have been developed but the occurring of resistance to these agents is oft...

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Detalles Bibliográficos
Autores principales: Bisaro, Brigitte, Sciortino, Marianna, Colombo, Shana, Leal, Maria Pilar Camacho, Costamagna, Andrea, Castellano, Isabella, Montemurro, Filippo, Rossi, Valentina, Valabrega, Giorgio, Turco, Emilia, Defilippi, Paola, Cabodi, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826217/
https://www.ncbi.nlm.nih.gov/pubmed/26716506
http://dx.doi.org/10.18632/oncotarget.6710

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