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The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer

Chromatin undergoes structural changes in response to extracellular and environmental signals. We observed changes in nuclear morphology in cancer tissue biopsied after chemotherapy and hypothesised that these DNA damage-induced changes are mediated by histone deacetylases (HDACs). Nuclear morpholog...

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Detalles Bibliográficos
Autores principales:	Huang, Rui, Langdon, Simon P, Tse, Matthew, Mullen, Peter, Um, In Hwa, Faratian, Dana, Harrison, David J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826236/ https://www.ncbi.nlm.nih.gov/pubmed/26683361 http://dx.doi.org/10.18632/oncotarget.6618

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