MicroRNA-584-3p, a novel tumor suppressor and prognostic marker, reduces the migration and invasion of human glioma cells by targeting hypoxia-induced ROCK1

Here, we report that microRNA-584-3p (miR-584-3p) is up-regulated in hypoxic glioma cells and in high-grade human glioma tumors (WHO grades III–IV) relative to normoxic cells and to low-grade tumors (WHO grades I–II), respectively. The postoperative survival time was significantly prolonged in the h...

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Detalles Bibliográficos
Autores principales: Xue, Hao, Guo, Xing, Han, Xiao, Yan, Shaofeng, Zhang, Jinsen, Xu, Shugang, Li, Tong, Guo, Xiaofan, Zhang, Ping, Gao, Xiao, Liu, Qinglin, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826243/
https://www.ncbi.nlm.nih.gov/pubmed/26715733
http://dx.doi.org/10.18632/oncotarget.6735

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