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PIG7 promotes leukemia cell chemosensitivity via lysosomal membrane permeabilization

PIG7 localizes to lysosomal membrane in leukemia cells. Our previous work has shown that transduction of pig7 into a series of leukemia cell lines did not result in either apoptosis or differentiation of most tested cell lines. Interestingly, it did significantly sensitize these cell lines to chemot...

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Detalles Bibliográficos
Autores principales: Liu, Jiazhuo, Peng, Leiwen, Niu, Ting, Wu, Yu, Li, Jianjun, Wang, Fangfang, Zheng, Yuhuan, Liu, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826247/
https://www.ncbi.nlm.nih.gov/pubmed/26716897
http://dx.doi.org/10.18632/oncotarget.6739