Adipocytes promote prostate cancer stem cell self-renewal through amplification of the cholecystokinin autocrine loop

Obesity has long been linked with prostate cancer progression, although the underlying mechanism is still largely unknown. Here, we report that adipocytes promote the enrichment of prostate cancer stem cells (CSCs) through a vicious cycle of autocrine amplification. In the presence of adipocytes, pr...

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Detalles Bibliográficos
Autores principales: Tang, Kai-Dun, Liu, Ji, Jovanovic, Lidija, An, Jiyuan, Hill, Michelle M., Vela, Ian, Lee, Terence Kin-Wah, Ma, Stephanie, Nelson, Colleen, Russell, Pamela J., Clements, Judith A., Ling, Ming-Tat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826255/
https://www.ncbi.nlm.nih.gov/pubmed/26700819
http://dx.doi.org/10.18632/oncotarget.6643

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