The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation

The Hippo signaling pathway is a major regulator of organ size. In the liver, Hippo pathway deregulation promotes hyperplasia and hepatocellular carcinoma primarily through hyperactivation of its downstream effector, YAP. The LATS2 tumor suppressor is a core member of the Hippo pathway. A screen for...

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Detalles Bibliográficos
Autores principales: Aylon, Yael, Gershoni, Anat, Rotkopf, Ron, Biton, Inbal E., Porat, Ziv, Koh, Anna P., Sun, Xiaochen, Lee, Youngmin, Fiel, Maria-Isabel, Hoshida, Yujin, Friedman, Scott L., Johnson, Randy L., Oren, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826395/
https://www.ncbi.nlm.nih.gov/pubmed/27013235
http://dx.doi.org/10.1101/gad.274167.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826395/
https://www.ncbi.nlm.nih.gov/pubmed/27013235
http://dx.doi.org/10.1101/gad.274167.115

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