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G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells

DNA methylation at imprinting control regions (ICRs) is established in gametes in a sex-specific manner and has to be stably maintained during development and in somatic cells to ensure the correct monoallelic expression of imprinted genes. In addition to DNA methylation, the ICRs are marked by alle...

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Detalles Bibliográficos
Autores principales: Zhang, Tuo, Termanis, Ausma, Özkan, Burak, Bao, Xun X., Culley, Jayne, de Lima Alves, Flavia, Rappsilber, Juri, Ramsahoye, Bernard, Stancheva, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826439/
https://www.ncbi.nlm.nih.gov/pubmed/27052169
http://dx.doi.org/10.1016/j.celrep.2016.03.007