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G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells
DNA methylation at imprinting control regions (ICRs) is established in gametes in a sex-specific manner and has to be stably maintained during development and in somatic cells to ensure the correct monoallelic expression of imprinted genes. In addition to DNA methylation, the ICRs are marked by alle...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826439/ https://www.ncbi.nlm.nih.gov/pubmed/27052169 http://dx.doi.org/10.1016/j.celrep.2016.03.007 |