The Timing of the Excitatory-to-Inhibitory GABA Switch Is Regulated by the Oxytocin Receptor via KCC2

Oxytocin and its receptor (Oxtr) play a crucial role in the postnatal transition of neuronal GABA neurotransmission from excitatory to inhibitory, a developmental process known as the GABA switch. Using hippocampal neurons from Oxtr-null mice, we show that (1) Oxtr is necessary for the correct timin...

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Detalles Bibliográficos
Autores principales: Leonzino, Marianna, Busnelli, Marta, Antonucci, Flavia, Verderio, Claudia, Mazzanti, Michele, Chini, Bice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826440/
https://www.ncbi.nlm.nih.gov/pubmed/27052180
http://dx.doi.org/10.1016/j.celrep.2016.03.013

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