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Titanium plate fixation versus conventional approach in the treatment of deep sternal wound infection

BACKGROUND: Deep sternal wound infection (DSWI) is a serious complication post cardiac surgery and associated with increased mortality, morbidity and cost. Sternal titanium plate fixation could be an effective approach to treat DSWI. We sought to compare the effectiveness of titanium plate fixation...

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Autores principales: Wang, Wei, Wang, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826514/
https://www.ncbi.nlm.nih.gov/pubmed/27059463
http://dx.doi.org/10.1186/s13019-016-0458-3
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author Wang, Wei
Wang, Shaohua
author_facet Wang, Wei
Wang, Shaohua
author_sort Wang, Wei
collection PubMed
description BACKGROUND: Deep sternal wound infection (DSWI) is a serious complication post cardiac surgery and associated with increased mortality, morbidity and cost. Sternal titanium plate fixation could be an effective approach to treat DSWI. We sought to compare the effectiveness of titanium plate fixation with conventional approach in the treatment of DSWI. METHODS: Retrospective data was analyzed from consecutive patients with DSWI post cardiac surgery who received either titanium plate fixation (sternal plate group) or conventional treatment with sternal debridement and rewiring (control group). Pre-operative risk factors and post-operative clinical outcome were compared between the 2 groups. RESULTS: A total of 36 patients (mean age 65.0 ± 8.6, 63.9 % male) with DSWI were in the sternal plate group whereas 26 patients (mean age 64.0 ± 13.4, 65.4 % male) were in the control group. The mean follow-up period was 15.92 months. The major pre-operative comorbidities were comparable between the 2 groups. The rate of receiving multiple debridement procedures (≥3) was significantly lower in the sternal plate group (5.6 % vs. 26.9 %, P = 0.03). Patients in the sternal plate group had no treatment failure, whereas 42.3 % of patients in the control group had treatment failure requiring muscle flaps reconstruction by plastic surgery (0 % vs. 42.3 %, P < 0.001). There was a trend of lower in-hospital mortality (11.1 % vs. 19.2 %, P = 0.47) in the sternal plate group. CONCLUSION: Compared to conventional treatment, titanium plate fixation appears to have favorable clinical outcome.
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spelling pubmed-48265142016-04-10 Titanium plate fixation versus conventional approach in the treatment of deep sternal wound infection Wang, Wei Wang, Shaohua J Cardiothorac Surg Research Article BACKGROUND: Deep sternal wound infection (DSWI) is a serious complication post cardiac surgery and associated with increased mortality, morbidity and cost. Sternal titanium plate fixation could be an effective approach to treat DSWI. We sought to compare the effectiveness of titanium plate fixation with conventional approach in the treatment of DSWI. METHODS: Retrospective data was analyzed from consecutive patients with DSWI post cardiac surgery who received either titanium plate fixation (sternal plate group) or conventional treatment with sternal debridement and rewiring (control group). Pre-operative risk factors and post-operative clinical outcome were compared between the 2 groups. RESULTS: A total of 36 patients (mean age 65.0 ± 8.6, 63.9 % male) with DSWI were in the sternal plate group whereas 26 patients (mean age 64.0 ± 13.4, 65.4 % male) were in the control group. The mean follow-up period was 15.92 months. The major pre-operative comorbidities were comparable between the 2 groups. The rate of receiving multiple debridement procedures (≥3) was significantly lower in the sternal plate group (5.6 % vs. 26.9 %, P = 0.03). Patients in the sternal plate group had no treatment failure, whereas 42.3 % of patients in the control group had treatment failure requiring muscle flaps reconstruction by plastic surgery (0 % vs. 42.3 %, P < 0.001). There was a trend of lower in-hospital mortality (11.1 % vs. 19.2 %, P = 0.47) in the sternal plate group. CONCLUSION: Compared to conventional treatment, titanium plate fixation appears to have favorable clinical outcome. BioMed Central 2016-04-08 /pmc/articles/PMC4826514/ /pubmed/27059463 http://dx.doi.org/10.1186/s13019-016-0458-3 Text en © Wang and Wang. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Wang, Wei
Wang, Shaohua
Titanium plate fixation versus conventional approach in the treatment of deep sternal wound infection
title Titanium plate fixation versus conventional approach in the treatment of deep sternal wound infection
title_full Titanium plate fixation versus conventional approach in the treatment of deep sternal wound infection
title_fullStr Titanium plate fixation versus conventional approach in the treatment of deep sternal wound infection
title_full_unstemmed Titanium plate fixation versus conventional approach in the treatment of deep sternal wound infection
title_short Titanium plate fixation versus conventional approach in the treatment of deep sternal wound infection
title_sort titanium plate fixation versus conventional approach in the treatment of deep sternal wound infection
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826514/
https://www.ncbi.nlm.nih.gov/pubmed/27059463
http://dx.doi.org/10.1186/s13019-016-0458-3
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