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Tranylcypromine, a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis

BACKGROUND: Growing evidence indicates that endometriosis is an epigenetic disease. Encouragingly, histone deacetylases (HDACs) and DNA methyltransferases have been shown to be promising targets by numerous in vitro studies. However, only a few studies have shown promising effects of HDAC inhibition...

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Detalles Bibliográficos
Autores principales:	Sun, Qunyan, Ding, Ding, Liu, Xishi, Guo, Sun-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826530/ https://www.ncbi.nlm.nih.gov/pubmed/27062244 http://dx.doi.org/10.1186/s12958-016-0154-0

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