Dabigatran in the Treatment of Warfarin-Induced Skin Necrosis: A New Hope

Warfarin-induced skin necrosis is an infrequent and well-recognized complication of warfarin treatment. The incidence was estimated between 0.01% and 0.1% whereas a paradoxal prothrombotic state that arises from warfarin therapy seems to be responsible for this life-threatening disease. To the best...

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Detalles Bibliográficos
Autores principales: Bakoyiannis, Christos, Karaolanis, Georgios, Patelis, Nikolaos, Maskanakis, Anastasios, Tsaples, Georgios, Klonaris, Christos, Georgopoulos, Sotirios, Liakakos, Theodoros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826711/
https://www.ncbi.nlm.nih.gov/pubmed/27110410
http://dx.doi.org/10.1155/2016/3121469
Descripción
Sumario:Warfarin-induced skin necrosis is an infrequent and well-recognized complication of warfarin treatment. The incidence was estimated between 0.01% and 0.1% whereas a paradoxal prothrombotic state that arises from warfarin therapy seems to be responsible for this life-threatening disease. To the best of our knowledge we present the first case of an old woman diagnosed with warfarin-induced skin necrosis, in whom novel oral anticoagulants and extensive surgical debridement were combined safely with excellent results.

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