Dabigatran in the Treatment of Warfarin-Induced Skin Necrosis: A New Hope

Warfarin-induced skin necrosis is an infrequent and well-recognized complication of warfarin treatment. The incidence was estimated between 0.01% and 0.1% whereas a paradoxal prothrombotic state that arises from warfarin therapy seems to be responsible for this life-threatening disease. To the best...

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Autores principales: Bakoyiannis, Christos, Karaolanis, Georgios, Patelis, Nikolaos, Maskanakis, Anastasios, Tsaples, Georgios, Klonaris, Christos, Georgopoulos, Sotirios, Liakakos, Theodoros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826711/
https://www.ncbi.nlm.nih.gov/pubmed/27110410
http://dx.doi.org/10.1155/2016/3121469
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author Bakoyiannis, Christos
Karaolanis, Georgios
Patelis, Nikolaos
Maskanakis, Anastasios
Tsaples, Georgios
Klonaris, Christos
Georgopoulos, Sotirios
Liakakos, Theodoros
author_facet Bakoyiannis, Christos
Karaolanis, Georgios
Patelis, Nikolaos
Maskanakis, Anastasios
Tsaples, Georgios
Klonaris, Christos
Georgopoulos, Sotirios
Liakakos, Theodoros
author_sort Bakoyiannis, Christos
collection PubMed
description Warfarin-induced skin necrosis is an infrequent and well-recognized complication of warfarin treatment. The incidence was estimated between 0.01% and 0.1% whereas a paradoxal prothrombotic state that arises from warfarin therapy seems to be responsible for this life-threatening disease. To the best of our knowledge we present the first case of an old woman diagnosed with warfarin-induced skin necrosis, in whom novel oral anticoagulants and extensive surgical debridement were combined safely with excellent results.
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spelling pubmed-48267112016-04-24 Dabigatran in the Treatment of Warfarin-Induced Skin Necrosis: A New Hope Bakoyiannis, Christos Karaolanis, Georgios Patelis, Nikolaos Maskanakis, Anastasios Tsaples, Georgios Klonaris, Christos Georgopoulos, Sotirios Liakakos, Theodoros Case Rep Dermatol Med Case Report Warfarin-induced skin necrosis is an infrequent and well-recognized complication of warfarin treatment. The incidence was estimated between 0.01% and 0.1% whereas a paradoxal prothrombotic state that arises from warfarin therapy seems to be responsible for this life-threatening disease. To the best of our knowledge we present the first case of an old woman diagnosed with warfarin-induced skin necrosis, in whom novel oral anticoagulants and extensive surgical debridement were combined safely with excellent results. Hindawi Publishing Corporation 2016 2016-03-27 /pmc/articles/PMC4826711/ /pubmed/27110410 http://dx.doi.org/10.1155/2016/3121469 Text en Copyright © 2016 Christos Bakoyiannis et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bakoyiannis, Christos
Karaolanis, Georgios
Patelis, Nikolaos
Maskanakis, Anastasios
Tsaples, Georgios
Klonaris, Christos
Georgopoulos, Sotirios
Liakakos, Theodoros
Dabigatran in the Treatment of Warfarin-Induced Skin Necrosis: A New Hope
title Dabigatran in the Treatment of Warfarin-Induced Skin Necrosis: A New Hope
title_full Dabigatran in the Treatment of Warfarin-Induced Skin Necrosis: A New Hope
title_fullStr Dabigatran in the Treatment of Warfarin-Induced Skin Necrosis: A New Hope
title_full_unstemmed Dabigatran in the Treatment of Warfarin-Induced Skin Necrosis: A New Hope
title_short Dabigatran in the Treatment of Warfarin-Induced Skin Necrosis: A New Hope
title_sort dabigatran in the treatment of warfarin-induced skin necrosis: a new hope
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826711/
https://www.ncbi.nlm.nih.gov/pubmed/27110410
http://dx.doi.org/10.1155/2016/3121469
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