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Mincle-mediated anti-inflammatory IL-10 response counter-regulates IL-12 in vitro

The role of macrophage-inducible C-type lectin (Mincle) in anti-inflammatory responses has not yet been fully characterized. Herein, we show that engagement of Mincle by trehalose-dimycolate or mycobacteria promotes IL-10 production in macrophages, which causes down-regulation of IL-12p40 secretion....

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Detalles Bibliográficos
Autores principales:	Patin, Emmanuel C, Willcocks, Sam, Orr, Selinda, Ward, Theresa H, Lang, Roland, Schaible, Ulrich E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826952/ https://www.ncbi.nlm.nih.gov/pubmed/26939595 http://dx.doi.org/10.1177/1753425916636671

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