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Effect of ankaferd blood stopper in experimental peritoneal adhesion model
PURPOSE: Ankaferd Blood Stopper (ABS) is an herbal extract attained from 5 different plants. It has the therapeutic potential to be used for the management of external hemorrhage and controlling gastrointestinal bleedings. To date, the safety of ABS for intraperitoneal usage is not clear. In this st...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Surgical Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826984/ https://www.ncbi.nlm.nih.gov/pubmed/27073792 http://dx.doi.org/10.4174/astr.2016.90.4.213 |
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author | Karaca, Gokhan Aydin, Oktay Pehlivanli, Faruk Kocael, Ahmet Pekcici, Recep Duymus, Esat Akgedik, Sukran Guler, Osman |
author_facet | Karaca, Gokhan Aydin, Oktay Pehlivanli, Faruk Kocael, Ahmet Pekcici, Recep Duymus, Esat Akgedik, Sukran Guler, Osman |
author_sort | Karaca, Gokhan |
collection | PubMed |
description | PURPOSE: Ankaferd Blood Stopper (ABS) is an herbal extract attained from 5 different plants. It has the therapeutic potential to be used for the management of external hemorrhage and controlling gastrointestinal bleedings. To date, the safety of ABS for intraperitoneal usage is not clear. In this study, we investigated the effectiveness and safety of using intraperitoneal ABS in an experimental peritoneal adhesion model. METHODS: Twenty-four male Wistar Albino rats were used in the study. The rats were randomly divided into 3 groups: saline, ABS, and control. On the 10th day, all rats were euthanized. The adhesions were evaluated by Nair's macroscopic adhesion classification, and pathologically evaluated with Zühlke's microscopic adhesion classification. RESULTS: macroscopic and microscopic comparison between the ABS and saline groups did not show any differences but both the ABS and saline groups were superior when compared to the control group. CONCLUSION: ABS was found equally effective with saline on the abdominal adhesions and to no effect on postoperative adhesion formation. |
format | Online Article Text |
id | pubmed-4826984 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Korean Surgical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-48269842016-04-12 Effect of ankaferd blood stopper in experimental peritoneal adhesion model Karaca, Gokhan Aydin, Oktay Pehlivanli, Faruk Kocael, Ahmet Pekcici, Recep Duymus, Esat Akgedik, Sukran Guler, Osman Ann Surg Treat Res Original Article PURPOSE: Ankaferd Blood Stopper (ABS) is an herbal extract attained from 5 different plants. It has the therapeutic potential to be used for the management of external hemorrhage and controlling gastrointestinal bleedings. To date, the safety of ABS for intraperitoneal usage is not clear. In this study, we investigated the effectiveness and safety of using intraperitoneal ABS in an experimental peritoneal adhesion model. METHODS: Twenty-four male Wistar Albino rats were used in the study. The rats were randomly divided into 3 groups: saline, ABS, and control. On the 10th day, all rats were euthanized. The adhesions were evaluated by Nair's macroscopic adhesion classification, and pathologically evaluated with Zühlke's microscopic adhesion classification. RESULTS: macroscopic and microscopic comparison between the ABS and saline groups did not show any differences but both the ABS and saline groups were superior when compared to the control group. CONCLUSION: ABS was found equally effective with saline on the abdominal adhesions and to no effect on postoperative adhesion formation. The Korean Surgical Society 2016-04 2016-03-30 /pmc/articles/PMC4826984/ /pubmed/27073792 http://dx.doi.org/10.4174/astr.2016.90.4.213 Text en Copyright © 2016, the Korean Surgical Society http://creativecommons.org/licenses/by-nc/4.0/ Annals of Surgical Treatment and Research is an Open Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Karaca, Gokhan Aydin, Oktay Pehlivanli, Faruk Kocael, Ahmet Pekcici, Recep Duymus, Esat Akgedik, Sukran Guler, Osman Effect of ankaferd blood stopper in experimental peritoneal adhesion model |
title | Effect of ankaferd blood stopper in experimental peritoneal adhesion model |
title_full | Effect of ankaferd blood stopper in experimental peritoneal adhesion model |
title_fullStr | Effect of ankaferd blood stopper in experimental peritoneal adhesion model |
title_full_unstemmed | Effect of ankaferd blood stopper in experimental peritoneal adhesion model |
title_short | Effect of ankaferd blood stopper in experimental peritoneal adhesion model |
title_sort | effect of ankaferd blood stopper in experimental peritoneal adhesion model |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826984/ https://www.ncbi.nlm.nih.gov/pubmed/27073792 http://dx.doi.org/10.4174/astr.2016.90.4.213 |
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