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TNF-α enhancement of CD62E mediates adhesion of non–small cell lung cancer cells to brain endothelium via CD15 in lung-brain metastasis

BACKGROUND: CD15, which is overexpressed on various cancers, has been reported as a cell adhesion molecule that plays a key role in non-CNS metastasis. However, the role of CD15 in brain metastasis is largely unexplored. This study provides a better understanding of CD15/CD62E interaction, enhanced...

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Detalles Bibliográficos
Autores principales:	Jassam, Samah A., Maherally, Zaynah, Smith, James R., Ashkan, Keyoumars, Roncaroli, Federico, Fillmore, Helen L., Pilkington, Geoffrey J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827040/ https://www.ncbi.nlm.nih.gov/pubmed/26472821 http://dx.doi.org/10.1093/neuonc/nov248

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