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Neural ablation of the PARK10 candidate Plpp3 leads to dopaminergic transmission deficits without neurodegeneration

Parkinson’s disease (PD) is a multifactorial neurodegenerative disorder, characterised by the progressive loss of midbrain dopaminergic neurons and a variety of motor symptoms. The gene coding for the phospholipid phosphatase 3, PLPP3 (formerly PPAP2B or LPP3), maps within the PARK10 locus, a region...

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Detalles Bibliográficos
Autores principales:	Gómez-López, Sandra, Martínez-Silva, Ana Valeria, Montiel, Teresa, Osorio-Gómez, Daniel, Bermúdez-Rattoni, Federico, Massieu, Lourdes, Escalante-Alcalde, Diana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827058/ https://www.ncbi.nlm.nih.gov/pubmed/27063549 http://dx.doi.org/10.1038/srep24028

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