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Nonmuscle Myosin IIA Regulates Intestinal Epithelial Barrier in vivo and Plays a Protective Role During Experimental Colitis
The actin cytoskeleton is a critical regulator of intestinal mucosal barrier permeability, and the integrity of epithelial adherens junctions (AJ) and tight junctions (TJ). Non muscle myosin II (NM II) is a key cytoskeletal motor that controls actin filament architecture and dynamics. While NM II ha...
Autores principales: | Naydenov, Nayden G., Feygin, Alex, Wang, Dongdong, Kuemmerle, John F., Harris, Gianni, Conti, Mary Anne, Adelstein, Robert S., Ivanov, Andrei I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827066/ https://www.ncbi.nlm.nih.gov/pubmed/27063635 http://dx.doi.org/10.1038/srep24161 |
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