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Current developments in toxicological research on arsenic
There is a plethora of recent publications on all aspects relevant to the toxicology of arsenic (As). Over centuries exposures to arsenic continue to be a major public health problem in many countries. In particular, the occurrence of high As concentrations in groundwater of Southeast Asia receives...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Leibniz Research Centre for Working Environment and Human Factors
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827077/ https://www.ncbi.nlm.nih.gov/pubmed/27092031 |
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author | Bolt, Hermann M. |
author_facet | Bolt, Hermann M. |
author_sort | Bolt, Hermann M. |
collection | PubMed |
description | There is a plethora of recent publications on all aspects relevant to the toxicology of arsenic (As). Over centuries exposures to arsenic continue to be a major public health problem in many countries. In particular, the occurrence of high As concentrations in groundwater of Southeast Asia receives now much attention. Therefore, arsenic is a high-priority matter for toxicological research. Key exposure to As are (traditional) medicines, combustion of As-rich coal, presence of As in groundwater, and pollution due to mining activities. As-induced cardiovascular disorders and carcinogenesis present themselves as a major research focus. The high priority of this issue is now recognized politically in a number of countries, research funds have been made available. Also experimental research on toxicokinetics and toxicodynamics and on modes of toxic action is moving very rapidly. The matter is of high regulatory concern, and effective preventive measures are required in a number of countries. |
format | Online Article Text |
id | pubmed-4827077 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Leibniz Research Centre for Working Environment and Human Factors |
record_format | MEDLINE/PubMed |
spelling | pubmed-48270772016-04-18 Current developments in toxicological research on arsenic Bolt, Hermann M. EXCLI J Review Article There is a plethora of recent publications on all aspects relevant to the toxicology of arsenic (As). Over centuries exposures to arsenic continue to be a major public health problem in many countries. In particular, the occurrence of high As concentrations in groundwater of Southeast Asia receives now much attention. Therefore, arsenic is a high-priority matter for toxicological research. Key exposure to As are (traditional) medicines, combustion of As-rich coal, presence of As in groundwater, and pollution due to mining activities. As-induced cardiovascular disorders and carcinogenesis present themselves as a major research focus. The high priority of this issue is now recognized politically in a number of countries, research funds have been made available. Also experimental research on toxicokinetics and toxicodynamics and on modes of toxic action is moving very rapidly. The matter is of high regulatory concern, and effective preventive measures are required in a number of countries. Leibniz Research Centre for Working Environment and Human Factors 2013-01-21 /pmc/articles/PMC4827077/ /pubmed/27092031 Text en Copyright © 2013 Bolt http://www.excli.de/documents/assignment_of_rights.pdf This is an Open Access article distributed under the following Assignment of Rights http://www.excli.de/documents/assignment_of_rights.pdf. You are free to copy, distribute and transmit the work, provided the original author and source are credited. |
spellingShingle | Review Article Bolt, Hermann M. Current developments in toxicological research on arsenic |
title | Current developments in toxicological research on arsenic |
title_full | Current developments in toxicological research on arsenic |
title_fullStr | Current developments in toxicological research on arsenic |
title_full_unstemmed | Current developments in toxicological research on arsenic |
title_short | Current developments in toxicological research on arsenic |
title_sort | current developments in toxicological research on arsenic |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827077/ https://www.ncbi.nlm.nih.gov/pubmed/27092031 |
work_keys_str_mv | AT bolthermannm currentdevelopmentsintoxicologicalresearchonarsenic |