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Generation of Hprt-disrupted rat through mouse←rat ES chimeras
We established rat embryonic stem (ES) cell lines from a double transgenic rat line which harbours CAG-GFP for ubiquitous expression of GFP in somatic cells and Acr3-EGFP for expression in sperm (green body and green sperm: GBGS rat). By injecting the GBGS rat ES cells into mouse blastocysts and tra...
Autores principales: | Isotani, Ayako, Yamagata, Kazuo, Okabe, Masaru, Ikawa, Masahito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827079/ https://www.ncbi.nlm.nih.gov/pubmed/27062982 http://dx.doi.org/10.1038/srep24215 |
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