Proximal ADP-ribose Hydrolysis in Trypanosomatids is Catalyzed by a Macrodomain

ADP-ribosylation is a ubiquitous protein modification utilized by both prokaryotes and eukaryotes for several cellular functions, such as DNA repair, proliferation, and cell signaling. Higher eukaryotes, such as humans, utilize various enzymes to reverse the modification and to regulate ADP-ribose d...

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Detalles Bibliográficos
Autores principales: Haikarainen, Teemu, Lehtiö, Lari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827093/
https://www.ncbi.nlm.nih.gov/pubmed/27064071
http://dx.doi.org/10.1038/srep24213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827093/
https://www.ncbi.nlm.nih.gov/pubmed/27064071
http://dx.doi.org/10.1038/srep24213

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