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Proximal ADP-ribose Hydrolysis in Trypanosomatids is Catalyzed by a Macrodomain
ADP-ribosylation is a ubiquitous protein modification utilized by both prokaryotes and eukaryotes for several cellular functions, such as DNA repair, proliferation, and cell signaling. Higher eukaryotes, such as humans, utilize various enzymes to reverse the modification and to regulate ADP-ribose d...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827093/ https://www.ncbi.nlm.nih.gov/pubmed/27064071 http://dx.doi.org/10.1038/srep24213 |