Cargando…
Low bone mass and changes in the osteocyte network in mice lacking autophagy in the osteoblast lineage
Autophagy maintains cell function and homeostasis by recycling intracellular components. This process is also required for morphological changes associated with maturation of some cell types. Osteoblasts are bone forming cells some of which become embedded in bone and differentiate into osteocytes....
Autores principales: | Piemontese, Marilina, Onal, Melda, Xiong, Jinhu, Han, Li, Thostenson, Jeff D., Almeida, Maria, O’Brien, Charles A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827128/ https://www.ncbi.nlm.nih.gov/pubmed/27064143 http://dx.doi.org/10.1038/srep24262 |
Ejemplares similares
-
Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone
por: Xiong, Jinhu, et al.
Publicado: (2015) -
Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence
por: Kim, Ha-Neui, et al.
Publicado: (2020) -
Deletion of a putative promoter-proximal Tnfsf11 regulatory region in mice does not alter bone mass or Tnfsf11 expression in vivo
por: MacLeod, Ryan S., et al.
Publicado: (2021) -
Loss of RANKL in osteocytes dramatically increases cancellous bone mass in the osteogenesis imperfecta mouse (oim)
por: Zimmerman, Sarah M., et al.
Publicado: (2018) -
Local Production of Osteoprotegerin by Osteoblasts Suppresses Bone Resorption
por: Cawley, Keisha M., et al.
Publicado: (2020)