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Current trends in oxysterol research

In this short review we provide a synopsis of recent developments in oxysterol research highlighting topics of current interest to the community. These include the involvement of oxysterols in neuronal development and survival, their participation in the immune system, particularly with respect to b...

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Detalles Bibliográficos
Autores principales: Griffiths, William J., Abdel-Khalik, Jonas, Hearn, Thomas, Yutuc, Eylan, Morgan, Alwena H., Wang, Yuqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827129/
https://www.ncbi.nlm.nih.gov/pubmed/27068984
http://dx.doi.org/10.1042/BST20150255
Descripción
Sumario:In this short review we provide a synopsis of recent developments in oxysterol research highlighting topics of current interest to the community. These include the involvement of oxysterols in neuronal development and survival, their participation in the immune system, particularly with respect to bacterial and viral infection and to T(h)17-cell development, and the role of oxysterols in breast cancer. We also discuss the value of oxysterol analysis in the diagnosis of disease.