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A comparison of methods to adjust for continuous covariates in the analysis of randomised trials
BACKGROUND: Although covariate adjustment in the analysis of randomised trials can be beneficial, adjustment for continuous covariates is complicated by the fact that the association between covariate and outcome must be specified. Misspecification of this association can lead to reduced power, and...
Autores principales: | Kahan, Brennan C., Rushton, Helen, Morris, Tim P., Daniel, Rhian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827223/ https://www.ncbi.nlm.nih.gov/pubmed/27068456 http://dx.doi.org/10.1186/s12874-016-0141-3 |
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