Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio

Energy dysfunction is associated with worse prognosis after traumatic brain injury (TBI). Recent data suggest that hypertonic sodium lactate infusion (HL) improves energy metabolism after TBI. Here, we specifically examined whether the efficacy of HL (3h infusion, 30–40 μmol/kg/min) in improving bra...

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Detalles Bibliográficos
Autores principales: Quintard, Hervé, Patet, Camille, Zerlauth, Jean-Baptiste, Suys, Tamarah, Bouzat, Pierre, Pellerin, Luc, Meuli, Reto, Magistretti, Pierre J., Oddo, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827289/
https://www.ncbi.nlm.nih.gov/pubmed/26421521
http://dx.doi.org/10.1089/neu.2015.4057

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