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Direct bone marrow HSC transplantation enhances local engraftment at the expense of systemic engraftment in NSG mice
Direct bone marrow (BM) injection has been proposed as a strategy to bypass homing inefficiencies associated with intravenous (IV) hematopoietic stem cell (HSC) transplantation. Despite physical delivery into the BM cavity, many donor cells are rapidly redistributed by vascular perfusion, perhaps co...
Autores principales: | Futrega, Kathryn, Lott, William B., Doran, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827391/ https://www.ncbi.nlm.nih.gov/pubmed/27065210 http://dx.doi.org/10.1038/srep23886 |
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