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Cancers in Young Patients in Uyo (Niger-delta Region of Nigeria): Magnitude of the Problem and Histopathological Prolife

Cancers are thought to be rarer in younger population, but emerging data show an increasing incidence of these diseases. The aim of this study was to evaluate the clinicopathological characteristics of cancer among young patients (≥30 years) in Uyo, Nigeria. All specimens were collected and reviewed...

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Autores principales: Abudu, Emmanuel Kunle, Akinbami, Oluyinka Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827647/
https://www.ncbi.nlm.nih.gov/pubmed/27134710
http://dx.doi.org/10.4081/rt.2016.6124
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author Abudu, Emmanuel Kunle
Akinbami, Oluyinka Samuel
author_facet Abudu, Emmanuel Kunle
Akinbami, Oluyinka Samuel
author_sort Abudu, Emmanuel Kunle
collection PubMed
description Cancers are thought to be rarer in younger population, but emerging data show an increasing incidence of these diseases. The aim of this study was to evaluate the clinicopathological characteristics of cancer among young patients (≥30 years) in Uyo, Nigeria. All specimens were collected and reviewed during the period January 2007-December 2012; complete clinicopathological data were also considered. A total of 108 cases of proven cancers were diagnosed (3.4%), accounting for 14.1% of all malignancies. A male:female ratio of 1:3.2 was recorded. Among 0-14-year-old patients, the most common malignancy was embryonal cancer (50.0%), followed by non-Hodgkin’s lymphoma (18.8%). Carcinoma of the breast and soft tissue sarcoma represent first and second cancers in those patients (40.7% and 13.0% respectively). Carcinoma of uterine cervix and nodal lymphomas were the third and fourth most common cancers respectively (10.2% and 7.4%), significantly higher in the 21-30 years and 0-10 years age groups. Invasive ductal carcinoma, squamous cell carcinoma, Kaposi sarcoma and Hodgkin’s lymphoma were the most common histologic types of cancers in breast, uterine cervix, lymph node and soft tissue (79.6%, 90.0%, 44.4%, 50.0% respectively). This study shows that embryonal cancer was the most common malignancy in patients aged 0 to 14, while carcinoma of the breast and soft tissue sarcoma were the two most common cancers in patients from 5 to 30 years-old.
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spelling pubmed-48276472016-04-29 Cancers in Young Patients in Uyo (Niger-delta Region of Nigeria): Magnitude of the Problem and Histopathological Prolife Abudu, Emmanuel Kunle Akinbami, Oluyinka Samuel Rare Tumors Article Cancers are thought to be rarer in younger population, but emerging data show an increasing incidence of these diseases. The aim of this study was to evaluate the clinicopathological characteristics of cancer among young patients (≥30 years) in Uyo, Nigeria. All specimens were collected and reviewed during the period January 2007-December 2012; complete clinicopathological data were also considered. A total of 108 cases of proven cancers were diagnosed (3.4%), accounting for 14.1% of all malignancies. A male:female ratio of 1:3.2 was recorded. Among 0-14-year-old patients, the most common malignancy was embryonal cancer (50.0%), followed by non-Hodgkin’s lymphoma (18.8%). Carcinoma of the breast and soft tissue sarcoma represent first and second cancers in those patients (40.7% and 13.0% respectively). Carcinoma of uterine cervix and nodal lymphomas were the third and fourth most common cancers respectively (10.2% and 7.4%), significantly higher in the 21-30 years and 0-10 years age groups. Invasive ductal carcinoma, squamous cell carcinoma, Kaposi sarcoma and Hodgkin’s lymphoma were the most common histologic types of cancers in breast, uterine cervix, lymph node and soft tissue (79.6%, 90.0%, 44.4%, 50.0% respectively). This study shows that embryonal cancer was the most common malignancy in patients aged 0 to 14, while carcinoma of the breast and soft tissue sarcoma were the two most common cancers in patients from 5 to 30 years-old. PAGEPress Publications, Pavia, Italy 2016-04-06 /pmc/articles/PMC4827647/ /pubmed/27134710 http://dx.doi.org/10.4081/rt.2016.6124 Text en ©Copyright E.K. Abudu and O.S. Akinbami http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Abudu, Emmanuel Kunle
Akinbami, Oluyinka Samuel
Cancers in Young Patients in Uyo (Niger-delta Region of Nigeria): Magnitude of the Problem and Histopathological Prolife
title Cancers in Young Patients in Uyo (Niger-delta Region of Nigeria): Magnitude of the Problem and Histopathological Prolife
title_full Cancers in Young Patients in Uyo (Niger-delta Region of Nigeria): Magnitude of the Problem and Histopathological Prolife
title_fullStr Cancers in Young Patients in Uyo (Niger-delta Region of Nigeria): Magnitude of the Problem and Histopathological Prolife
title_full_unstemmed Cancers in Young Patients in Uyo (Niger-delta Region of Nigeria): Magnitude of the Problem and Histopathological Prolife
title_short Cancers in Young Patients in Uyo (Niger-delta Region of Nigeria): Magnitude of the Problem and Histopathological Prolife
title_sort cancers in young patients in uyo (niger-delta region of nigeria): magnitude of the problem and histopathological prolife
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827647/
https://www.ncbi.nlm.nih.gov/pubmed/27134710
http://dx.doi.org/10.4081/rt.2016.6124
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