C. elegans miro-1 Mutation Reduces the Amount of Mitochondria and Extends Life Span

Mitochondria play a critical role in aging, however, the underlying mechanism is not well understood. We found that a mutation disrupting the C. elegans homolog of Miro GTPase (miro-1) extends life span. This phenotype requires simultaneous loss of miro-1 from multiple tissues including muscles and...

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Detalles Bibliográficos
Autores principales: Shen, Yanqing, Ng, Li Fang, Low, Natarie Pei Wen, Hagen, Thilo, Gruber, Jan, Inoue, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827821/
https://www.ncbi.nlm.nih.gov/pubmed/27064409
http://dx.doi.org/10.1371/journal.pone.0153233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827821/
https://www.ncbi.nlm.nih.gov/pubmed/27064409
http://dx.doi.org/10.1371/journal.pone.0153233

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