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Pentosan Polysulfate: Oral Versus Subcutaneous Injection in Mucopolysaccharidosis Type I Dogs

BACKGROUND: We previously demonstrated the therapeutic benefits of pentosan polysulfate (PPS) in a rat model of mucopolysaccharidosis (MPS) type VI. Reduction of inflammation, reduction of glycosaminoglycan (GAG) storage, and improvement in the skeletal phenotype were shown. Herein, we evaluate the...

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Detalles Bibliográficos
Autores principales:	Simonaro, Calogera M., Tomatsu, Shunji, Sikora, Tracy, Kubaski, Francyne, Frohbergh, Michael, Guevara, Johana M., Wang, Raymond Y., Vera, Moin, Kang, Jennifer L., Smith, Lachlan J., Schuchman, Edward H., Haskins, Mark E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827827/ https://www.ncbi.nlm.nih.gov/pubmed/27064989 http://dx.doi.org/10.1371/journal.pone.0153136

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