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Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing
[Image: see text] The formation of reactive oxygen species (ROS) is linked to the pathogenesis of neurodegenerative diseases. Here we have investigated the effect of soluble and aggregated amyloid-β (Aβ) and α-synuclein (αS), associated with Alzheimer’s and Parkinson’s diseases, respectively, on the...
Autores principales: | Pedersen, Jeppe T., Chen, Serene W., Borg, Christian B., Ness, Samuel, Bahl, Justyna M., Heegaard, Niels H. H., Dobson, Christopher M., Hemmingsen, Lars, Cremades, Nunilo, Teilum, Kaare |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2016
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827876/ https://www.ncbi.nlm.nih.gov/pubmed/26967463 http://dx.doi.org/10.1021/jacs.5b13577 |
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