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Profile of acotiamide in the treatment of functional dyspepsia
Efficacy of acotiamide for improving symptoms in patients with functional dyspepsia was shown by several clinical trials. In a randomized, double-blind, placebo-controlled, parallel-group comparative Phase III trial conducted in Japan, 100 mg of acotiamide three times a day for 4 weeks was more effe...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827886/ https://www.ncbi.nlm.nih.gov/pubmed/27103837 http://dx.doi.org/10.2147/CEG.S72172 |
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author | Ueda, Masahiro Iwasaki, Eisuke Suzuki, Hidekazu |
author_facet | Ueda, Masahiro Iwasaki, Eisuke Suzuki, Hidekazu |
author_sort | Ueda, Masahiro |
collection | PubMed |
description | Efficacy of acotiamide for improving symptoms in patients with functional dyspepsia was shown by several clinical trials. In a randomized, double-blind, placebo-controlled, parallel-group comparative Phase III trial conducted in Japan, 100 mg of acotiamide three times a day for 4 weeks was more effective than a placebo for improving symptoms, and quality of life. Acotiamide was well-tolerated treatment, with no significant adverse events. The aim of this review was to summarize the current evidence of the efficacy of acotiamide in the treatment of patients with functional dyspepsia. |
format | Online Article Text |
id | pubmed-4827886 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-48278862016-04-21 Profile of acotiamide in the treatment of functional dyspepsia Ueda, Masahiro Iwasaki, Eisuke Suzuki, Hidekazu Clin Exp Gastroenterol Review Efficacy of acotiamide for improving symptoms in patients with functional dyspepsia was shown by several clinical trials. In a randomized, double-blind, placebo-controlled, parallel-group comparative Phase III trial conducted in Japan, 100 mg of acotiamide three times a day for 4 weeks was more effective than a placebo for improving symptoms, and quality of life. Acotiamide was well-tolerated treatment, with no significant adverse events. The aim of this review was to summarize the current evidence of the efficacy of acotiamide in the treatment of patients with functional dyspepsia. Dove Medical Press 2016-04-06 /pmc/articles/PMC4827886/ /pubmed/27103837 http://dx.doi.org/10.2147/CEG.S72172 Text en © 2016 Ueda et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Review Ueda, Masahiro Iwasaki, Eisuke Suzuki, Hidekazu Profile of acotiamide in the treatment of functional dyspepsia |
title | Profile of acotiamide in the treatment of functional dyspepsia |
title_full | Profile of acotiamide in the treatment of functional dyspepsia |
title_fullStr | Profile of acotiamide in the treatment of functional dyspepsia |
title_full_unstemmed | Profile of acotiamide in the treatment of functional dyspepsia |
title_short | Profile of acotiamide in the treatment of functional dyspepsia |
title_sort | profile of acotiamide in the treatment of functional dyspepsia |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827886/ https://www.ncbi.nlm.nih.gov/pubmed/27103837 http://dx.doi.org/10.2147/CEG.S72172 |
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