Cargando…

CXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis

Elevated CXCL13 within the central nervous system (CNS) correlates with humoral responses in several neuroinflammatory diseases, yet its role is controversial. During coronavirus encephalomyelitis CXCL13 deficiency impaired CNS accumulation of memory B cells and antibody-secreting cells (ASC) but no...

Descripción completa

Detalles Bibliográficos
Autores principales:	Phares, Timothy W., DiSano, Krista D., Stohlman, Stephen A., Segal, Benjamin M., Bergmann, Cornelia C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. Published by Elsevier Inc. 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828287/ https://www.ncbi.nlm.nih.gov/pubmed/26795429 http://dx.doi.org/10.1016/j.bbi.2016.01.016

Ejemplares similares

Dynamics of B cell subsets within the CNS during viral encephalomyelitis
por: Disano, Krista, et al.
Publicado: (2014)

Activated GL7(+) B cells are maintained within the inflamed CNS in the absence of follicle formation during viral encephalomyelitis
por: DiSano, Krista D., et al.
Publicado: (2017)

IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis
por: Phares, Timothy W., et al.
Publicado: (2013)

An optimized method for enumerating CNS derived memory B cells during viral-induced inflammation
por: DiSano, Krista D., et al.
Publicado: (2017)

Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis
por: Valentin-Torres, Alice, et al.
Publicado: (2016)

Are CSF CXCL13 concentrations solely dependent on intrathecal production? A commentary on “Chemokine CXCL13 in serum, CSF, and blood–CSF barrier function”
por: DiSano, Krista D., et al.
Publicado: (2021)

Differential Regulation of Self-reactive CD4(+) T Cells in Cervical Lymph Nodes and Central Nervous System during Viral Encephalomyelitis
por: Savarin, Carine, et al.
Publicado: (2016)

Intrathecally produced CXCL13: A predictive biomarker in multiple sclerosis
por: DiSano, Krista D, et al.
Publicado: (2020)

Enhanced CD8 T-cell anti-viral function and clinical disease in B7-H1-deficient mice requires CD4 T cells during encephalomyelitis
por: Phares, Timothy W, et al.
Publicado: (2012)

Distinct CD4 T-cell effects on primary versus recall CD8 T-cell responses during viral encephalomyelitis
por: Hwang, Mihyun, et al.
Publicado: (2015)

PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis
por: Kapil, Parul, et al.
Publicado: (2014)

MMP-independent role of TIMP-1 at the blood brain barrier during viral encephalomyelitis
por: Savarin, Carine, et al.
Publicado: (2013)

Role of CD25(+) CD4(+) T cells in acute and persistent coronavirus infection of the central nervous system
por: de Aquino, Maria Teresa P., et al.
Publicado: (2013)

IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils
por: Savarin, Carine, et al.
Publicado: (2012)

Central Nervous System Inflammatory Aggregates in the Theiler's Virus Model of Progressive Multiple Sclerosis
por: DiSano, Krista D., et al.
Publicado: (2019)

Coronavirus infection of the central nervous system: host–virus stand-off
por: Bergmann, Cornelia C., et al.
Publicado: (2006)

Intrathecal Humoral Immunity to Encephalitic RNA Viruses
por: Phares, Timothy W., et al.
Publicado: (2013)

MMP9 deficiency does not decrease blood–brain barrier disruption, but increases astrocyte MMP3 expression during viral encephalomyelitis
por: Savarin, Carine, et al.
Publicado: (2011)

Regulated Production of CXCL13 within the Central Nervous System
por: Irani, David N.
Publicado: (2016)

The lymphoid chemokine, CXCL13, is dispensable for the initial recruitment of B cells to the acutely inflamed central nervous system
por: Rainey-Barger, Emily K., et al.
Publicado: (2011)

Acute RNA Viral Encephalomyelitis and the Role of Antibodies in the Central Nervous System
por: Bartlett, Maggie L., et al.
Publicado: (2020)

Kinetics of Cytokine mRNA Expression in the Central Nervous System Following Lethal and Nonlethal Coronavirus-Induced Acute Encephalomyelitis
por: Parra, Beatriz, et al.
Publicado: (1997)

CXCL13 and CXCL9 CSF Levels in Central Nervous System Lymphoma—Diagnostic, Therapeutic, and Prognostic Relevance
por: Masouris, Ilias, et al.
Publicado: (2021)

Mouse hepatitis virus pathogenesis in the central nervous system is independent of IL-15 and natural killer cells
por: Zuo, Jun, et al.
Publicado: (2006)

Studies on the mechanism of protection from acute viral encephalomyelitis by delayed-type hypersensitivity inducer T cell clones
por: Erlich, Stephanie S., et al.
Publicado: (1989)

Evidence for Class-Specific Factors in Immunoglobulin Isotype Switching
por: Shanmugam, Ananth, et al.
Publicado: (2000)

Antigen structural requirements for immunoglobulin isotype switching in mice
por: Chen, P, et al.
Publicado: (1980)

Loop extrusion promotes an alternate pathway for isotype switching
por: Shen, Hong Ming, et al.
Publicado: (2021)

Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis
por: Savarin, Carine, et al.
Publicado: (2015)

Self-reactive CD4(+) T cells activated during viral-induced demyelination do not prevent clinical recovery
por: Savarin, Carine, et al.
Publicado: (2015)

TACI and BAFF-R mediate isotype switching in B cells
por: Castigli, Emanuela, et al.
Publicado: (2005)

The Liaison of Isotype Class Switch and Mismatch Repair: An Illegitimate Affair
por: Kenter, Amy L.
Publicado: (1999)

Viral Encephalomyelitis
por: Griffin, Diane E.
Publicado: (2011)

B cell differentiation and isotype switching is related to division cycle number
Publicado: (1996)

Idiotope regulation by isotype switch variants of two monoclonal antiidiotope antibodies
Publicado: (1984)

Ikaros controls isotype selection during immunoglobulin class switch recombination
por: Sellars, MacLean, et al.
Publicado: (2009)

Antibody Isotype Switching as a Mechanism to Counter HIV Neutralization Escape
por: Scheepers, Cathrine, et al.
Publicado: (2020)

SeXX Matters in Multiple Sclerosis
por: Gilli, Francesca, et al.
Publicado: (2020)

Memory B Cells in Multiple Sclerosis: Emerging Players in Disease Pathogenesis
por: DiSano, Krista D., et al.
Publicado: (2021)

Alpha/Beta Interferon (IFN-α/β) Signaling in Astrocytes Mediates Protection against Viral Encephalomyelitis and Regulates IFN-γ-Dependent Responses
por: Hwang, Mihyun, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_cbquh3gossjc8p9pjv9sc0vir2