Leishmania infantum Genetic Diversity and Lutzomyia longipalpis Mitochondrial Haplotypes in Brazil

Leishmania infantum is the etiological agent of visceral leishmaniasis (VL) in the Americas with domestic dogs being its major reservoir hosts. The main VL vector is the sandfly Lutzomyia longipalpis, while other Lutzomyia species may play a role in disease transmission. Although the genetic structu...

Descripción completa

Detalles Bibliográficos
Autores principales: Ribolla, Paulo Eduardo Martins, Gushi, Letícia Tsieme, Pires e Cruz, Maria do Socorro, Costa, Carlos Henrique Nery, Costa, Dorcas Lamounier, Lima Júnior, Manoel Sebastião da Costa, Dorval, Maria Elizabeth Moraes Cavalheiros, Gutierrez de Oliveira, Alessandra, da Cunha Santos, Mirella Ferreira, Fonseca Camargo-Neves, Vera Lúcia, Fortaleza, Carlos Magno Castello Branco, Alonso, Diego Peres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828539/
https://www.ncbi.nlm.nih.gov/pubmed/27119085
http://dx.doi.org/10.1155/2016/9249217
Descripción
Sumario:Leishmania infantum is the etiological agent of visceral leishmaniasis (VL) in the Americas with domestic dogs being its major reservoir hosts. The main VL vector is the sandfly Lutzomyia longipalpis, while other Lutzomyia species may play a role in disease transmission. Although the genetic structure of L. infantum populations has been widely evaluated, only a few studies have addressed this subject coupled to the genetic structure of the respective sandfly vectors. In this study, we analyzed the population structure of L. infantum in three major VL endemic areas in Brazil and associated it with Lutzomyia longipalpis geographic structure.

Ejemplares similares